| Protein Name | zinc finger protein 420 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 147923 |
| Gene Symbol | ZNF420 |
| UniProt | Q8TAQ5 (ZN420_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
9
Total Number of Articles : 3 |
Description |
zinc finger protein 420 |
| Gene Summary |
The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016] |
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| Properties | |