Protein Name NCK interacting protein with SH3 domain
Organism Homo sapiens
Gene ID 51517
Gene Symbol

NCKIPSD

UniProt Q9NZQ3 (SPN90_HUMAN)
Relationships Total Number of functionally related compound(s) : 78
Total Number of Articles : 59
Description

NCK interacting protein with SH3 domain

Gene Summary

The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019]

synonyms
  • NCK-interacting protein with SH3 domain
  • 54 kDa VacA-interacting protein
  • 54 kDa vimentin-interacting protein
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Properties