Protein Name | NCK interacting protein with SH3 domain |
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Organism | Homo sapiens |
Gene ID | 51517 |
Gene Symbol | NCKIPSD |
UniProt | Q9NZQ3 (SPN90_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
78
Total Number of Articles : 59 |
Description |
NCK interacting protein with SH3 domain |
Gene Summary |
The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019] |
synonyms |
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Properties | |