Protein Name ATPase copper transporting alpha
Organism Danio rerio
Gene ID 564924
Gene Symbol

atp7a

UniProt Q4F8H5 (Q4F8H5_DANRE), F1QEG1 (F1QEG1_DANRE)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 16
Description

ATPase copper transporting alpha

Gene Summary

Predicted to enable P-type divalent copper transporter activity and copper ion binding activity. Acts upstream of or within response to copper ion. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in plasma membrane and trans-Golgi network. Is expressed in digestive system; gill; locus coeruleus; neural tube; and notochord. Used to study Menkes disease. Human ortholog(s) of this gene implicated in Menkes disease; X-linked distal spinal muscular atrophy 3; cutis laxa; and occipital horn syndrome. Orthologous to human ATP7A (ATPase copper transporting alpha). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • copper-transporting ATPase 1
  • ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)
  • Menkes disease ATPase
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Properties