Protein Name FA complementation group G
Organism Homo sapiens
Gene ID 2189
Gene Symbol

FANCG

UniProt O15287 (FANCG_HUMAN), Q53XM5 (Q53XM5_HUMAN)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 33
Description

FA complementation group G

Gene Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008]

synonyms
  • Fanconi anemia group G protein
  • DNA repair protein XRCC9
  • Fanconi anemia complementation group G
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Properties