| Protein Name | SMAD family member 5 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 17129 |
| Gene Symbol | Smad5 |
| UniProt | P97454 (SMAD5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
18
Total Number of Articles : 17 |
Description |
SMAD family member 5 |
| Gene Summary |
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including SMAD protein signal transduction; negative regulation of transcription by RNA polymerase II; and ureteric bud development. Acts upstream of or within several processes, including osteoblast fate commitment; skeletal system development; and transforming growth factor beta receptor superfamily signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; egg cylinder; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human SMAD5 (SMAD family member 5). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |