Protein Name microsomal triglyceride transfer protein
Organism Danio rerio
Gene ID 406207
Gene Symbol

mttp

UniProt A0A0R4IVV0 (MTP_DANRE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 5
Description

microsomal triglyceride transfer protein

Gene Summary

Enables lipid transfer activity. Involved in lipoprotein transport. Acts upstream of or within several processes, including fatty acid transport; lipoprotein biosynthetic process; and sprouting angiogenesis. Predicted to be active in Golgi apparatus; basolateral plasma membrane; and endoplasmic reticulum. Is expressed in several structures, including gut; liver; marginal blastomere; testis; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including abetalipoproteinemia; familial hypercholesterolemia; hyperinsulinism; metabolic dysfunction-associated steatotic liver disease; and obesity. Orthologous to human MTTP (microsomal triglyceride transfer protein). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • microsomal triglyceride transfer protein large subunit
  • stalactite
  • mtp
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Properties