Protein Name protein kinase C, delta
Organism Rattus norvegicus
Gene ID 170538
Gene Symbol

Prkcd

UniProt P09215 (KPCD_RAT)
Relationships Total Number of functionally related compound(s) : 96
Total Number of Articles : 89
Description

protein kinase C, delta

Gene Summary

Enables TIR domain binding activity; diacylglycerol-dependent, calcium-independent serine/threonine kinase activity; and protein serine/threonine kinase binding activity. Involved in several processes, including D-aspartate import across plasma membrane; positive regulation of D-glucose import; and positive regulation of MAP kinase activity. Is active in postsynaptic cytosol. Used to study brain ischemia and hypertension. Biomarker of hyperinsulinism; hypertension; muscular disease; obesity; and restrictive cardiomyopathy. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3 and steatotic liver disease. Orthologous to human PRKCD (protein kinase C delta). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • protein kinase C delta type
  • nPKC-delta
  • Pkcd
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Properties