| Protein Name | neurogenin 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11925 |
| Gene Symbol | Neurog3 |
| UniProt | P70661 (NGN3_MOUSE), Q548G3 (Q548G3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
29
Total Number of Articles : 38 |
Description |
neurogenin 3 |
| Gene Summary |
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in positive regulation of DNA-templated transcription and transdifferentiation. Acts upstream of or within epithelial cell differentiation; positive regulation of transcription by RNA polymerase II; and regulation of dendrite morphogenesis. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in congenital malabsorptive diarrhea 4; glucose intolerance; and type 2 diabetes mellitus. Orthologous to human NEUROG3 (neurogenin 3). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |