Protein Name | KLF transcription factor 8 |
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Organism | Homo sapiens |
Gene ID | 11279 |
Gene Symbol | KLF8 |
UniProt | O95600 (KLF8_HUMAN), A0A024R9X4 (A0A024R9X4_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
25
Total Number of Articles : 21 |
Description |
KLF transcription factor 8 |
Gene Summary |
This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
synonyms |
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Properties | |