Protein Name KLF transcription factor 8
Organism Homo sapiens
Gene ID 11279
Gene Symbol

KLF8

UniProt O95600 (KLF8_HUMAN), A0A024R9X4 (A0A024R9X4_HUMAN)
Relationships Total Number of functionally related compound(s) : 25
Total Number of Articles : 21
Description

KLF transcription factor 8

Gene Summary

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

synonyms
  • Krueppel-like factor 8
  • Kruppel like factor 8
  • basic krueppel-like factor 3
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Properties