Protein Name ubiquilin 2
Organism Mus musculus
Gene ID 54609
Gene Symbol

Ubqln2

UniProt Q9QZM0 (UBQL2_MOUSE)
Relationships Total Number of functionally related compound(s) : 5
Total Number of Articles : 3
Description

ubiquilin 2

Gene Summary

Predicted to enable identical protein binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including negative regulation of receptor-mediated endocytosis; regulation of cellular catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in cytosol. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 15. Orthologous to human UBQLN2 (ubiquilin 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • ubiquilin-2
  • Ubiquitin-related protein
  • protein linking IAP with cytoskeleton 2
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Properties