| Protein Name | purinergic receptor P2X, ligand-gated ion channel, 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 228139 |
| Gene Symbol | P2rx3 |
| UniProt | Q3UR32 (P2RX3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
40
Total Number of Articles : 51 |
Description |
purinergic receptor P2X, ligand-gated ion channel, 3 |
| Gene Summary |
Enables extracellularly ATP-gated monoatomic cation channel activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within several processes, including neuromuscular synaptic transmission; response to ATP; and smooth muscle contraction. Located in axon. Is active in Schaffer collateral - CA1 synapse and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including branchial arch; embryo ectoderm; gut; nervous system; and retina. Orthologous to human P2RX3 (purinergic receptor P2X 3). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |