| Protein Name | Discoidin domain receptor |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 3346209 |
| Gene Symbol | Ddr |
| UniProt | Q59DZ7 (Q59DZ7_DROME), E1JHA2 (E1JHA2_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 5 |
Description |
Discoidin domain receptor |
| Gene Summary |
Predicted to enable collagen binding activity and protein tyrosine kinase collagen receptor activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of neuron projection development; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including alcoholic liver cirrhosis; bone disease (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and skin melanoma. Orthologous to several human genes including DDR1 (discoidin domain receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |