| Protein Name | Excitatory amino acid transporter 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 34251 |
| Gene Symbol | Eaat1 |
| UniProt | O77062 (O77062_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
10
Total Number of Articles : 11 |
Description |
Excitatory amino acid transporter 1 |
| Gene Summary |
Enables L-aspartate transmembrane transporter activity; L-glutamate transmembrane transporter activity; and glutamate:sodium symporter activity. Involved in several processes, including adult locomotory behavior; determination of adult lifespan; and regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction. Located in terminal bouton. Colocalizes with neuromuscular junction. Is expressed in adult head; adult heart; nervous system; and protocerebrum. Used to study episodic ataxia type 6 and neurodegenerative disease. Human ortholog(s) of this gene implicated in dicarboxylic aminoaciduria; episodic ataxia type 6; and schizophrenia 18. Orthologous to several human genes including SLC1A3 (solute carrier family 1 member 3). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
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| Properties | |