Protein Name Tubby protein homolog 1
Organism Caenorhabditis elegans
Gene ID 174312
Gene Symbol

tub-1

UniProt Q09306 (TUB1_CAEEL)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 4
Description

Tubby protein homolog 1

Gene Summary

Involved in positive regulation of neurogenesis and receptor localization to non-motile cilium. Located in cytoplasm; non-motile cilium; and periciliary membrane compartment. Is expressed in neurons. Used to study obesity. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 15; retinitis pigmentosa; and retinitis pigmentosa 14. Orthologous to several human genes including TUB (TUB bipartite transcription factor) and TULP3 (TUB like protein 3). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Tubby protein homolog 1
  • CELE_F10B5.4
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Properties