Protein Name macrophage migration inhibitory factor
Organism Rattus norvegicus
Gene ID 81683
Gene Symbol

Mif

UniProt P30904 (MIF_RAT), A0A0F7RQL3 (A0A0F7RQL3_RAT)
Relationships Total Number of functionally related compound(s) : 201
Total Number of Articles : 170
Description

macrophage migration inhibitory factor

Gene Summary

Predicted to enable several functions, including identical protein binding activity; intramolecular oxidoreductase activity; and receptor ligand activity. Involved in several processes, including positive regulation of transport; response to steroid hormone; and response to vitamin. Located in cytoplasm; extracellular space; and nucleus. Used to study several diseases, including acute necrotizing pancreatitis; cardiomyopathy (multiple); lung disease (multiple); retinitis; and toxic shock syndrome. Biomarker of borna disease; cystitis; kidney disease; myocardial infarction; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in allergic disease; asthma; cystic fibrosis; lung disease (multiple); and obesity. Orthologous to human MIF (macrophage migration inhibitory factor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • macrophage migration inhibitory factor
  • L-dopachrome isomerase
  • L-dopachrome tautomerase
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Properties