| Protein Name | aldo-keto reductase family 1, member C14 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 191574 |
| Gene Symbol | Akr1c14 |
| UniProt | P23457 (DIDH_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
221
Total Number of Articles : 140 |
Description |
aldo-keto reductase family 1, member C14 |
| Gene Summary |
Enables steroid dehydrogenase activity. Involved in androgen catabolic process; hippocampus development; and response to resveratrol. Located in cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; alcohol dependence; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |