Protein Name aldo-keto reductase family 1, member C14
Organism Rattus norvegicus
Gene ID 191574
Gene Symbol

Akr1c14

UniProt P23457 (DIDH_RAT)
Relationships Total Number of functionally related compound(s) : 221
Total Number of Articles : 140
Description

aldo-keto reductase family 1, member C14

Gene Summary

Enables steroid dehydrogenase activity. Involved in hippocampus development. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to several human genes including AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 3-alpha-hydroxysteroid dehydrogenase
  • 3-alpha-HSD
  • hydroxyprostaglandin dehydrogenase
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Properties