| Protein Name | carbohydrate sulfotransferase 11 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 50515 |
| Gene Symbol | CHST11 |
| UniProt | Q9NPF2 (CHSTB_HUMAN), A0A024RBL0 (A0A024RBL0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
31
Total Number of Articles : 33 |
Description |
carbohydrate sulfotransferase 11 |
| Gene Summary |
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
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