| Protein Name | epidermal growth factor receptor pathway substrate 8 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13860 |
| Gene Symbol | Eps8 |
| UniProt | Q08509 (EPS8_MOUSE), Q3U2Z5 (Q3U2Z5_MOUSE), Q3UFL4 (Q3UFL4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
14
Total Number of Articles : 13 |
Description |
epidermal growth factor receptor pathway substrate 8 |
| Gene Summary |
Enables actin binding activity and small GTPase binding activity. Involved in several processes, including Rac protein signal transduction; actin filament organization; and barbed-end actin filament capping. Acts upstream of or within several processes, including actin cytoskeleton reorganization; behavioral response to ethanol; and cellular response to leukemia inhibitory factor. Located in several cellular components, including brush border; ruffle membrane; and stereocilium tip. Part of NMDA selective glutamate receptor complex. Is expressed in several structures, including adrenal gland; alimentary system; bone; brain; and metanephros. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (epidermal growth factor receptor pathway substrate 8). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
|
| Properties | |