Protein Name | acyl-CoA thioesterase 11 |
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Organism | Homo sapiens |
Gene ID | 26027 |
Gene Symbol | ACOT11 |
UniProt | Q8WXI4 (ACO11_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
20
Total Number of Articles : 11 |
Description |
acyl-CoA thioesterase 11 |
Gene Summary |
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] |
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