Protein Name acyl-CoA thioesterase 11
Organism Homo sapiens
Gene ID 26027
Gene Symbol

ACOT11

UniProt Q8WXI4 (ACO11_HUMAN)
Relationships Total Number of functionally related compound(s) : 20
Total Number of Articles : 11
Description

acyl-CoA thioesterase 11

Gene Summary

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]

synonyms
  • acyl-coenzyme A thioesterase 11
  • START domain containing 14
  • StAR-related lipid transfer (START) domain containing 14
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Properties