Protein Name translocated promoter region, nuclear basket protein
Organism Homo sapiens
Gene ID 7175
Gene Symbol


UniProt P12270 (TPR_HUMAN)
Relationships Total Number of functionally related compound(s) : 238
Total Number of Articles : 210

translocated promoter region, nuclear basket protein

Gene Summary

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008]

  • nucleoprotein TPR
  • NPC-associated intranuclear protein
  • megator
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