Protein Name | polypeptide N-acetylgalactosaminyltransferase 7 |
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Organism | Homo sapiens |
Gene ID | 51809 |
Gene Symbol | GALNT7 |
UniProt | Q86SF2 (GALT7_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 7 |
Description |
polypeptide N-acetylgalactosaminyltransferase 7 |
Gene Summary |
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |