Protein Name polypeptide N-acetylgalactosaminyltransferase 7
Organism Homo sapiens
Gene ID 51809
Gene Symbol

GALNT7

UniProt Q86SF2 (GALT7_HUMAN)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 7
Description

polypeptide N-acetylgalactosaminyltransferase 7

Gene Summary

This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008]

synonyms
  • N-acetylgalactosaminyltransferase 7
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
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Properties