Protein Name | centromeric DNA-binding histone H3-like protein CSE4 |
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Organism | Saccharomyces cerevisiae S288C |
Gene ID | 853817 |
Gene Symbol | CSE4 |
UniProt | P36012 (CENPA_YEAST) |
Relationships |
Total Number of functionally related compound(s) :
17
Total Number of Articles : 23 |
Description |
centromeric DNA-binding histone H3-like protein CSE4 |
Gene Summary |
Enables centromeric DNA binding activity. Involved in 2-micrometer plasmid partitioning; chromosome organization; and protein localization to CENP-A containing chromatin. Located in 2-micrometer circle DNA; condensed chromosome, centromeric region; and peroxisome. Part of CENP-A containing nucleosome. Is active in kinetochore. Used to study cancer; male infertility; and oligospermia. Human ortholog(s) of this gene implicated in autoimmune disease. Orthologous to human CENPA (centromere protein A). [provided by Alliance of Genome Resources, Jun 2025] |
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