Protein Name glycogen phosphorylase B
Organism Homo sapiens
Gene ID 5834
Gene Symbol

PYGB

UniProt P11216 (PYGB_HUMAN)
Relationships Total Number of functionally related compound(s) : 119
Total Number of Articles : 119
Description

glycogen phosphorylase B

Gene Summary

The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]

synonyms
  • glycogen phosphorylase, brain form
  • phosphorylase, glycogen; brain
  • GPBB
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Properties