Protein Name cathepsin H
Organism Homo sapiens
Gene ID 1512
Gene Symbol

CTSH

UniProt P09668 (CATH_HUMAN), E9PKT6 (E9PKT6_HUMAN)
Relationships Total Number of functionally related compound(s) : 81
Total Number of Articles : 41
Description

cathepsin H

Gene Summary

The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

synonyms
  • pro-cathepsin H
  • N-benzoylarginine-beta-naphthylamide hydrolase
  • aleurain
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Properties