Protein Name NADH dehydrogenase (ubiquinone) 23 kDa subunit
Organism Drosophila melanogaster
Gene ID 44207
Gene Symbol

ND-23

UniProt Q9VF27 (NDUS8_DROME)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 3
Description

NADH dehydrogenase (ubiquinone) 23 kDa subunit

Gene Summary

Predicted to enable 4 iron, 4 sulfur cluster binding activity and oxidoreductase activity, acting on NAD(P)H. Predicted to contribute to NADH dehydrogenase (ubiquinone) activity and NADH dehydrogenase activity. Involved in mitochondrial ATP synthesis coupled electron transport. Located in mitochondrion. Part of respiratory chain complex I. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; epithelial tube; gut section; and larval muscle cell. Used to study Leigh disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • NADH dehydrogenase (ubiquinone) 23 kDa subunit
  • CG3944-PA
  • COMPLEX I: 23 kDa subunit
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Properties