Protein Name ankyrin repeat domain 27
Organism Homo sapiens
Gene ID 84079
Gene Symbol

ANKRD27

UniProt Q96NW4 (ANR27_HUMAN)
Relationships Total Number of functionally related compound(s) : 7
Total Number of Articles : 6
Description

ankyrin repeat domain 27

Gene Summary

Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endocytic recycling and negative regulation of SNARE complex assembly. Acts upstream of or within early endosome to late endosome transport. Located in several cellular components, including cytosol; endosome; and lysosome. Implicated in eosinophilic esophagitis. [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • ankyrin repeat domain-containing protein 27
  • VPS9 domain-containing protein
  • VPS9-ankyrin-repeat protein
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Properties