Protein Name prostaglandin-endoperoxide synthase 2a
Organism Danio rerio
Gene ID 246227
Gene Symbol

ptgs2a

UniProt Q8JH43 (Q8JH43_DANRE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 8
Description

prostaglandin-endoperoxide synthase 2a

Gene Summary

Enables peroxidase activity. Acts upstream of or within several processes, including embryonic liver development; exocrine pancreas development; and pronephros development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including cardiovascular system; digestive system; gonad; head; and trigeminal placode. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; arthritis (multiple); cardiovascular system disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • prostaglandin G/H synthase 2a
  • Cox-2a
  • cox2
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Properties