Protein Name molybdenum cofactor synthesis 2
Organism Homo sapiens
Gene ID 4338
Gene Symbol

MOCS2

UniProt O96033 (MOC2A_HUMAN), O96007 (MOC2B_HUMAN), A0A024QZS1 (A0A024QZS1_HUMAN)
Relationships Total Number of functionally related compound(s) : 12
Total Number of Articles : 6
Description

molybdenum cofactor synthesis 2

Gene Summary

Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]

synonyms
  • molybdopterin synthase catalytic subunit
  • molybdopterin synthase sulfur carrier subunit
  • molybdenum cofactor biosynthesis protein E
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Properties