CPRiL

Protein Name	heat shock protein 90 alpha family class B member 1
Organism	Rattus norvegicus
Gene ID	301252
Gene Symbol	Hsp90ab1
UniProt	P34058 (HS90B_RAT)
Relationships	Total Number of functionally related compound(s) : 19 Total Number of Articles : 17
Description	heat shock protein 90 alpha family class B member 1
Gene Summary	Enables several functions, including nucleotide binding activity; sulfonylurea receptor binding activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of complement-dependent cytotoxicity; positive regulation of cell size; and regulation of protein metabolic process. Located in several cellular components, including basolateral plasma membrane; brush border membrane; and sperm head plasma membrane. Part of protein folding chaperone complex. Biomarker of muscular atrophy; pancreatitis; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to several human genes including HSP90AB1 (heat shock protein 90 alpha family class B member 1). [provided by Alliance of Genome Resources, Jul 2025]
synonyms	heat shock protein HSP 90-beta HSP 84 HSP84 heat shock 84 kDa heat shock 90kDa protein 1, beta heat shock protein 90 alpha (cytosolic), class B member 1 heat shock protein 90kDa alpha (cytosolic), class B member 1 heat shock protein 90kDa alpha family class B member 1 HSP90-BETA HSP90B HSPC2 Hspcb Click to show/hide the synonyms
Properties