Protein Name carbohydrate sulfotransferase 4
Organism Homo sapiens
Gene ID 10164
Gene Symbol

CHST4

UniProt Q8NCG5 (CHST4_HUMAN)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 14
Description

carbohydrate sulfotransferase 4

Gene Summary

This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]

synonyms
  • carbohydrate sulfotransferase 4
  • GST-3
  • HEC-GlcNAc6ST
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Properties