Protein Name interleukin 10 receptor, alpha
Organism Mus musculus
Gene ID 16154
Gene Symbol

Il10ra

UniProt Q61727 (I10R1_MOUSE), Q3UDL4 (Q3UDL4_MOUSE), H3BKN6 (H3BKN6_MOUSE), Q3U6I9 (Q3U6I9_MOUSE), Q3UDV8 (Q3UDV8_MOUSE), Q3UE89 (Q3UE89_MOUSE)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 28
Description

interleukin 10 receptor, alpha

Gene Summary

Predicted to enable interleukin-10 binding activity and interleukin-10 receptor activity. Predicted to be involved in several processes, including intestinal epithelial structure maintenance; positive regulation of receptor signaling pathway via JAK-STAT; and ubiquitin-dependent endocytosis. Predicted to act upstream of or within interleukin-10-mediated signaling pathway. Predicted to be located in cilium; cytosol; and nucleoplasm. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • interleukin-10 receptor subunit alpha
  • IL-10 receptor subunit alpha
  • IL-10R subunit 1
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Properties