Protein Name exostosin glycosyltransferase 2
Organism Mus musculus
Gene ID 14043
Gene Symbol

Ext2

UniProt P70428 (EXT2_MOUSE), Q3UDB5 (Q3UDB5_MOUSE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 17
Description

exostosin glycosyltransferase 2

Gene Summary

Enables acetylglucosaminyltransferase activity; glucuronosyltransferase activity; and protein homodimerization activity. Acts upstream of or within with a positive effect on gene expression; protein N-linked glycosylation; and sulfation. Acts upstream of or within several processes, including heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; and sodium ion homeostasis. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and respiratory system. Used to study hereditary multiple exostoses. Orthologous to human EXT2 (exostosin glycosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • exostosin-2
  • exostoses (multiple) 2
  • glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
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Properties