| Protein Name | solute carrier family 9 (sodium/hydrogen exchanger), member 6 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 236794 |
| Gene Symbol | Slc9a6 |
| UniProt | A1L3P4 (A1L3P4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
7
Total Number of Articles : 6 |
Description |
solute carrier family 9 (sodium/hydrogen exchanger), member 6 |
| Gene Summary |
Enables potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in regulation of intracellular pH and regulation of postsynaptic membrane neurotransmitter receptor levels. Acts upstream of or within several processes, including brain-derived neurotrophic factor receptor signaling pathway; dendritic spine development; and regulation of neurotrophin TRK receptor signaling pathway. Located in several cellular components, including axon; dendrite; and endosome. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Used to study Christianson syndrome. Human ortholog(s) of this gene implicated in Christianson syndrome. Orthologous to human SLC9A6 (solute carrier family 9 member A6). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |