Protein Name mitochondrial pyruvate carrier 1
Organism Mus musculus
Gene ID 55951
Gene Symbol

Mpc1

UniProt P63030 (MPC1_MOUSE), Q3UX28 (Q3UX28_MOUSE), D3Z5S0 (D3Z5S0_MOUSE)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 19
Description

mitochondrial pyruvate carrier 1

Gene Summary

Contributes to pyruvate transmembrane transporter activity. Acts upstream of or within cellular response to leukemia inhibitory factor; mitochondrial acetyl-CoA biosynthetic process from pyruvate; and mitochondrial pyruvate transmembrane transport. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; hemolymphoid system; nervous system; olfactory epithelium; and retina. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • mitochondrial pyruvate carrier 1
  • apoptosis-regulating basic protein
  • brain protein 44-like protein
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Properties