Protein Name ubiquitin protein ligase E3 component n-recognin 7
Organism Homo sapiens
Gene ID 55148
Gene Symbol

UBR7

UniProt Q8N806 (UBR7_HUMAN)
Relationships Total Number of functionally related compound(s) : 5
Total Number of Articles : 3
Description

ubiquitin protein ligase E3 component n-recognin 7

Gene Summary

This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]

synonyms
  • putative E3 ubiquitin-protein ligase UBR7
  • N-recognin-7
  • RING-type E3 ubiquitin transferase UBR7
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Properties