| Protein Name | haptoglobin-related protein |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3250 |
| Gene Symbol | HPR |
| UniProt | P00739 (HPTR_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
339
Total Number of Articles : 446 |
Description |
haptoglobin-related protein |
| Gene Summary |
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011] |
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| Properties | |