Protein Name deleted in malignant brain tumors 1
Organism Mus musculus
Gene ID 12945
Gene Symbol

Dmbt1

UniProt Q60997 (DMBT1_MOUSE)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 19
Description

deleted in malignant brain tumors 1

Gene Summary

Enables zymogen binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Acts upstream of or within inner cell mass cell proliferation; positive regulation of epithelial cell differentiation; and response to bacterium. Located in extracellular matrix and zymogen granule membrane. Is expressed in several structures, including blastocyst; central nervous system; genitourinary system; gut; and notochord. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human DMBT1 (deleted in malignant brain tumors 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • scavenger receptor cysteine-rich domain-containing protein DMBT1
  • deleted in malignant brain tumors 1 protein
  • apactin
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Properties