Protein Name solute carrier family 39 (metal ion transporter), member 8
Organism Mus musculus
Gene ID 67547
Gene Symbol

Slc39a8

UniProt Q91W10 (S39A8_MOUSE)
Relationships Total Number of functionally related compound(s) : 26
Total Number of Articles : 39
Description

solute carrier family 39 (metal ion transporter), member 8

Gene Summary

Enables anion:cation symporter activity and transition metal ion transmembrane transporter activity. Involved in bicarbonate transport; cellular transition metal ion homeostasis; and ion transmembrane transport. Acts upstream of or within cadmium ion transmembrane transport. Located in apical plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; metanephros; and reproductive system. Used to study left ventricular noncompaction. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • metal cation symporter ZIP8
  • Zrt- and Irt-like protein 8
  • zinc transporter ZIP8
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Properties