Protein Name | protein tyrosine phosphatase, receptor type Z1 |
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Organism | Rattus norvegicus |
Gene ID | 25613 |
Gene Symbol | Ptprz1 |
UniProt | Q62656 (PTPRZ_RAT), F1LMY3 (F1LMY3_RAT) |
Relationships |
Total Number of functionally related compound(s) :
10
Total Number of Articles : 14 |
Description |
protein tyrosine phosphatase, receptor type Z1 |
Gene Summary |
Enables fibroblast growth factor binding activity and protein tyrosine phosphatase activity. Involved in several processes, including nervous system development; positive regulation of cell migration; and regulation of dendrite development. Located in several cellular components, including lamellipodium; perineuronal net; and ruffle membrane. Is intrinsic component of plasma membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Biomarker of amyotrophic lateral sclerosis; middle cerebral artery infarction; status epilepticus; temporal lobe epilepsy; and visual epilepsy. Orthologous to human PTPRZ1 (protein tyrosine phosphatase receptor type Z1). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |