Protein Name protein tyrosine phosphatase, receptor type Z1
Organism Rattus norvegicus
Gene ID 25613
Gene Symbol

Ptprz1

UniProt Q62656 (PTPRZ_RAT), F1LMY3 (F1LMY3_RAT)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 14
Description

protein tyrosine phosphatase, receptor type Z1

Gene Summary

Enables fibroblast growth factor binding activity and protein tyrosine phosphatase activity. Involved in several processes, including nervous system development; positive regulation of cell migration; and regulation of dendrite development. Located in several cellular components, including lamellipodium; perineuronal net; and ruffle membrane. Is intrinsic component of plasma membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Biomarker of amyotrophic lateral sclerosis; middle cerebral artery infarction; status epilepticus; temporal lobe epilepsy; and visual epilepsy. Orthologous to human PTPRZ1 (protein tyrosine phosphatase receptor type Z1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • receptor-type tyrosine-protein phosphatase zeta
  • 3F8 chondroitin sulfate proteoglycan
  • 3H1 keratan sulfate proteoglycan
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Properties