Protein Name beta galactoside alpha 2,6 sialyltransferase 1
Organism Mus musculus
Gene ID 20440
Gene Symbol

St6gal1

UniProt Q64685 (SIAT1_MOUSE), Q8BM62 (Q8BM62_MOUSE)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 43
Description

beta galactoside alpha 2,6 sialyltransferase 1

Gene Summary

This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Nov 2011]

synonyms
  • beta-galactoside alpha-2,6-sialyltransferase 1
  • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1
  • ST6Gal I
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Properties