Protein Name calcitonin related polypeptide alpha
Organism Homo sapiens
Gene ID 796
Gene Symbol

CALCA

UniProt P06881 (CALCA_HUMAN), P01258 (CALC_HUMAN)
Relationships Total Number of functionally related compound(s) : 784
Total Number of Articles : 1590
Description

calcitonin related polypeptide alpha

Gene Summary

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]

synonyms
  • calcitonin
  • calcitonin gene-related peptide 1
  • alpha-type CGRP
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Properties