Protein Name G protein subunit alpha q;Guanine nucleotide-binding protein G(Q) subunit alpha;Guanine nucleotide-binding protein alpha-q
Organism Caenorhabditis elegans
Gene ID 171751
Gene Symbol

egl-30

UniProt G5EGU1 (G5EGU1_CAEEL), X5LQ30 (X5LQ30_CAEEL)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 14
Description

G protein subunit alpha q;Guanine nucleotide-binding protein G(Q) subunit alpha;Guanine nucleotide-binding protein alpha-q

Gene Summary

Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including cellular response to dopamine; positive regulation of protein localization; and regulation of secretion. Located in axon; cytoplasm; and neuronal cell body. Is extrinsic component of cytoplasmic side of plasma membrane. Is expressed widely. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; autosomal dominant hypocalcemia 2; congestive heart failure; familial hypocalciuric hypercalcemia 2; and familial multiple nevi flammei. Orthologous to several human genes including GNA11 (G protein subunit alpha 11). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • G protein subunit alpha q;Guanine nucleotide-binding protein G(Q) subunit alpha;Guanine nucleotide-binding protein alpha-q
  • CELE_M01D7.7
Click to show/hide the synonyms
Properties