Protein Name | G protein subunit alpha q;Guanine nucleotide-binding protein G(Q) subunit alpha;Guanine nucleotide-binding protein alpha-q |
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Organism | Caenorhabditis elegans |
Gene ID | 171751 |
Gene Symbol | egl-30 |
UniProt | G5EGU1 (G5EGU1_CAEEL), X5LQ30 (X5LQ30_CAEEL) |
Relationships |
Total Number of functionally related compound(s) :
11
Total Number of Articles : 14 |
Description |
G protein subunit alpha q;Guanine nucleotide-binding protein G(Q) subunit alpha;Guanine nucleotide-binding protein alpha-q |
Gene Summary |
Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including cellular response to dopamine; positive regulation of protein localization; and regulation of secretion. Located in axon; cytoplasm; and neuronal cell body. Is extrinsic component of cytoplasmic side of plasma membrane. Is expressed widely. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; autosomal dominant hypocalcemia 2; congestive heart failure; familial hypocalciuric hypercalcemia 2; and familial multiple nevi flammei. Orthologous to several human genes including GNA11 (G protein subunit alpha 11). [provided by Alliance of Genome Resources, Apr 2022] |
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