| Protein Name | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 57531 |
| Gene Symbol | HACE1 |
| UniProt | Q8IYU2 (HACE1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
17
Total Number of Articles : 17 |
Description |
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 |
| Gene Summary |
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016] |
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| Properties | |