| Protein Name | fat |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 33627 |
| Gene Symbol | ft |
| UniProt | P33450 (FAT_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
21
Total Number of Articles : 21 |
Description |
fat |
| Gene Summary |
Enables cadherin binding activity and calcium ion binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; establishment of planar polarity; and imaginal disc development. Located in apicolateral plasma membrane. Is integral component of plasma membrane. Is expressed in several structures, including ectoderm; embryonic/larval gut; extended germ band embryo; eye; and presumptive embryonic/larval system. Used to study carcinoma and neurodegenerative disease. Human ortholog(s) of this gene implicated in Hennekam syndrome and Van Maldergem syndrome 2. Orthologous to human FAT4 (FAT atypical cadherin 4). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |