Protein Name | BCL2-antagonist/killer 1 |
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Organism | Rattus norvegicus |
Gene ID | 116502 |
Gene Symbol | Bak1 |
UniProt | Q9JK59 (Q9JK59_RAT) |
Relationships |
Total Number of functionally related compound(s) :
48
Total Number of Articles : 39 |
Description |
BCL2-antagonist/killer 1 |
Gene Summary |
Enables several functions, including heat shock protein binding activity; identical protein binding activity; and protein-folding chaperone binding activity. Involved in several processes, including positive regulation of release of cytochrome c from mitochondria; release of cytochrome c from mitochondria; and response to hydrogen peroxide. Located in cytoplasm. Biomarker of intermittent claudication. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1). [provided by Alliance of Genome Resources, Jul 2025] |
synonyms |
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Properties | |