Protein Name BCL2-antagonist/killer 1
Organism Rattus norvegicus
Gene ID 116502
Gene Symbol

Bak1

UniProt Q9JK59 (Q9JK59_RAT)
Relationships Total Number of functionally related compound(s) : 48
Total Number of Articles : 39
Description

BCL2-antagonist/killer 1

Gene Summary

Enables several functions, including heat shock protein binding activity; identical protein binding activity; and protein-folding chaperone binding activity. Involved in several processes, including positive regulation of release of cytochrome c from mitochondria; release of cytochrome c from mitochondria; and response to hydrogen peroxide. Located in cytoplasm. Biomarker of intermittent claudication. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • bcl-2 homologous antagonist/killer
  • Bak
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Properties