CPRiL

Protein Name	Inositol 1,4,5,-trisphosphate receptor
Organism	Drosophila melanogaster
Gene ID	40664
Gene Symbol	Itpr
UniProt	P29993 (ITPR_DROME), A0A0B4LGN1 (A0A0B4LGN1_DROME)
Relationships	Total Number of functionally related compound(s) : 39 Total Number of Articles : 49
Description	Inositol 1,4,5,-trisphosphate receptor
Gene Summary	Enables inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. Involved in several processes, including fatty acid homeostasis; larval feeding behavior; and positive regulation of cytosolic calcium ion concentration. Located in axonal growth cone and smooth endoplasmic reticulum. Is expressed in several structures, including adult thoracic segment; head; imaginal disc; mesoderm; and somatic precursor cell. Used to study obesity. Human ortholog(s) of this gene implicated in Gillespie syndrome; isolated anhidrosis with normal sweat glands; neurodegenerative disease (multiple); and type 1 diabetes mellitus. Orthologous to several human genes including ITPR1 (inositol 1,4,5-trisphosphate receptor type 1). [provided by Alliance of Genome Resources, Apr 2022]
synonyms	inositol 1,4,5,-trisphosphate receptor 1, 4, 5-inositol trisphosphate receptor CG1063-PA CG1063-PB CG1063-PC IP3 receptor IP[[3]] receptor Inositol(1,4,5)-triphosphate receptor 42B Ins(1,4,5)P[[3]] receptor InsP[[3]] receptor Itpr-PA Itpr-PB Itpr-PC dm_IP3 receptor inositol 1,4,5,-tris-phosphate receptor inositol 1,4,5-triphosphate receptor inositol 1,4,5-trisphosphate (InsP3) receptor inositol 1,4,5-trisphosphate receptor inositol triphosphate receptor 1 inositol trisphosphate receptor inositol-1,3,5,-trisphosphate receptor inositol-1,4,5-trisphosphate receptor inositol-triphosphate receptor ip3-receptor type 1 InsP{3} receptor Dmel_CG1063 CG1063 DIP DmInsP[[3R]] DmInsP[[3]]R Click to show/hide the synonyms
Properties