| Protein Name | G protein signaling modulator 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 29899 |
| Gene Symbol | GPSM2 |
| UniProt | P81274 (GPSM2_HUMAN), A0A024R0F8 (A0A024R0F8_HUMAN), B4DIF1 (B4DIF1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
99
Total Number of Articles : 50 |
Description |
G protein signaling modulator 2 |
| Gene Summary |
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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