Protein Name ATPase, Ca++ transporting, plasma membrane 2
Organism Mus musculus
Gene ID 11941
Gene Symbol

Atp2b2

UniProt Q9R0K7 (AT2B2_MOUSE), Q3UHH0 (Q3UHH0_MOUSE), Q3UHJ3 (Q3UHJ3_MOUSE), F8WHB1 (F8WHB1_MOUSE)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 35
Description

ATPase, Ca++ transporting, plasma membrane 2

Gene Summary

Enables calcium-dependent ATPase activity. Involved in cochlea development and regulation of cytosolic calcium ion concentration. Acts upstream of or within several processes, including animal organ development; cGMP metabolic process; and detection of mechanical stimulus involved in sensory perception of sound. Located in several cellular components, including apical plasma membrane; endoplasmic reticulum; and neuronal cell body. Is expressed in heart; labyrinthine zone; liver; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • plasma membrane calcium-transporting ATPase 2
  • deaf waddler
  • plasma membrane calcium ATPase
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Properties