Protein Name | ATPase, Ca++ transporting, plasma membrane 2 |
---|---|
Organism | Mus musculus |
Gene ID | 11941 |
Gene Symbol | Atp2b2 |
UniProt | Q9R0K7 (AT2B2_MOUSE), Q3UHH0 (Q3UHH0_MOUSE), Q3UHJ3 (Q3UHJ3_MOUSE), F8WHB1 (F8WHB1_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
19
Total Number of Articles : 35 |
Description |
ATPase, Ca++ transporting, plasma membrane 2 |
Gene Summary |
Enables calcium-dependent ATPase activity. Involved in cochlea development and regulation of cytosolic calcium ion concentration. Acts upstream of or within several processes, including animal organ development; cGMP metabolic process; and detection of mechanical stimulus involved in sensory perception of sound. Located in several cellular components, including apical plasma membrane; endoplasmic reticulum; and neuronal cell body. Is expressed in heart; labyrinthine zone; liver; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
|
Properties | |