Protein Name telomerase reverse transcriptase
Organism Danio rerio
Gene ID 796551
Gene Symbol

tert

UniProt A2THE9 (A2THE9_DANRE)
Relationships Total Number of functionally related compound(s) : 4
Total Number of Articles : 3
Description

telomerase reverse transcriptase

Gene Summary

Enables telomerase activity. Acts upstream of or within several processes, including intestinal epithelial structure maintenance; negative regulation of cellular senescence; and telomere maintenance via telomerase. Located in nucleus. Is expressed in several structures, including brain; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant dyskeratosis congenita 2; carcinoma (multiple); gastrointestinal stromal tumor; leukemia (multiple); and melanoma (multiple). Orthologous to human TERT (telomerase reverse transcriptase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • telomerase reverse transcriptase
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Properties