Protein Name Suppressor of variegation 205
Organism Drosophila melanogaster
Gene ID 34119
Gene Symbol

Su(var)205

UniProt P05205 (HP1_DROME)
Relationships Total Number of functionally related compound(s) : 20
Total Number of Articles : 31
Description

Suppressor of variegation 205

Gene Summary

Enables several functions, including Hsp70 protein binding activity; RNA polymerase II C-terminal domain binding activity; and sequence-specific double-stranded DNA binding activity. Involved in several processes, including positive regulation of FACT complex assembly; protein localization to euchromatin; and regulatory ncRNA-mediated heterochromatin formation. Located in chromosome and nucleus. Colocalizes with polytene chromosome interband and polytene chromosome puff. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; ganglia; and gonad. Orthologous to human CBX1 (chromobox 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • suppressor of variegation 205
  • C1A9-nuclear-antigen
  • CG8409-PA
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Properties